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Correlation of Higher Antibody Levels to Pneumococcal Proteins with Protection from Pneumococcal Acute Otitis Media but not Protection from Nasopharyngeal Colonization in Young Children
OBJECTIVES: We previously found that nasopharyngeal (NP) colonization by Streptococcus pneumoniae (Spn) elicits mucosal antibody responses to three protein vaccine candidates: pneumococcal histidine triad protein D (PhtD), pneumococcal choline binding protein A (PcpA), and detoxified pneumolysin (Pl...
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| Опубликовано в: : | Clin Microbiol Infect |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505501/ https://ncbi.nlm.nih.gov/pubmed/28143785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmi.2017.01.011 |
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