H(2)S Production by Reactive Oxygen Species in the Carotid Body Triggers Hypertension in a Rodent Model of Sleep Apnea

Sleep apnea is a prevalent respiratory disease in which episodic cessation of breathing causes intermittent hypoxia. Patients with sleep apnea and rodents exposed to intermittent hypoxia exhibit hypertension. The carotid body senses changes in blood O(2) concentrations and an enhanced carotid body c...

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Pubblicato in:Sci Signal
Autori principali: Yuan, Guoxiang, Peng, Ying-Jie, Khan, Shakil A., Nanduri, Jayasri, Singh, Amritha, Vasavda, Chirag, Semenza, Gregg L., Kumar, Ganesh K., Snyder, Solomon H., Prabhakar, Nanduri R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505181/
https://ncbi.nlm.nih.gov/pubmed/27531649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaf3204
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