Protein kinase G–regulated production of H(2)S governs oxygen sensing

Reflexes initiated by the carotid body, the principal O(2)-sensing organ, are critical for maintaining cardio-respiratory homeostasis during hypoxia. O(2) sensing by the carotid body requires carbon monoxide (CO) generation by heme oxygenase-2 (HO-2) and hydrogen sulfide (H(2)S) synthesis by cystath...

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Publicado en:Sci Signal
Autores principales: Yuan, Guoxiang, Vasavda, Chirag, Peng, Ying-Jie, Makarenko, Vladislav V., Raghuraman, Gayatri, Nanduri, Jayasri, Gadalla, Moataz M., Semenza, Gregg L., Kumar, Ganesh K., Snyder, Solomon H., Prabhakar, Nanduri R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418480/
https://ncbi.nlm.nih.gov/pubmed/25900831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005846
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