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Triptolide exerts protective effects against fibrosis following ileocolonic anastomosis by mechanisms involving the miR-16-1/HSP70 pathway in IL-10-deficient mice

Surgeries, particularly ileocecal resection (ICR), are often required in the treatment of Crohn's disease (CD). However, recurrences are common for patients who undergo ICR, and anastomotic fibrosis is the main cause of re-operation. The present study aimed to investigate the therapeutic effect...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Hou, Hong-Wei, Wang, Jin-Min, Wang, Dong, Wu, Rong, Ji, Zhen-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505014/
https://ncbi.nlm.nih.gov/pubmed/28627592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.3016
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