Aldose Reductase Inhibitor Protects against Hyperglycemic Stress by Activating Nrf2-Dependent Antioxidant Proteins

We have shown earlier that pretreatment of cultured cells with aldose reductase (AR) inhibitors prevents hyperglycemia-induced mitogenic and proinflammatory responses. However, the effects of AR inhibitors on Nrf2-mediated anti-inflammatory responses have not been elucidated yet. We have investigate...

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Detalles Bibliográficos
Publicado en:J Diabetes Res
Autores principales: Shukla, Kirtikar, Pal, Pabitra Bikash, Sonowal, Himangshu, Srivastava, Satish K., Ramana, Kota V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2017
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504933/
https://ncbi.nlm.nih.gov/pubmed/28740855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/6785852
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