Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

BACKGROUND: The underlying biological mechanisms through which epidemiologically defined breast cancer risk factors contribute to disease risk remain poorly understood. Identification of the molecular changes associated with cancer risk factors in normal tissues may aid in determining the earliest e...

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Gepubliceerd in:Breast Cancer Res
Hoofdauteurs: Johnson, Kevin C., Houseman, E. Andres, King, Jessica E., Christensen, Brock C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504720/
https://ncbi.nlm.nih.gov/pubmed/28693600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0873-y
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