Normal breast tissue DNA methylation differences at regulatory elements are associated with the cancer risk factor age

BACKGROUND: The underlying biological mechanisms through which epidemiologically defined breast cancer risk factors contribute to disease risk remain poorly understood. Identification of the molecular changes associated with cancer risk factors in normal tissues may aid in determining the earliest e...

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Veröffentlicht in:Breast Cancer Res
Hauptverfasser: Johnson, Kevin C., Houseman, E. Andres, King, Jessica E., Christensen, Brock C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504720/
https://ncbi.nlm.nih.gov/pubmed/28693600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-017-0873-y
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