Oxalate-induced chronic kidney disease with its uremic and cardiovascular complications in C57BL/6 mice

Chronic kidney disease (CKD) research is limited by the lack of convenient inducible models mimicking human CKD and its complications in experimental animals. We demonstrate that a soluble oxalate-rich diet induces stable stages of CKD in male and female C57BL/6 mice. Renal histology is characterize...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Mulay, Shrikant R., Eberhard, Jonathan N., Pfann, Victoria, Marschner, Julian A., Darisipudi, Murthy N., Daniel, Christoph, Romoli, Simone, Desai, Jyaysi, Grigorescu, Melissa, Kumar, Santhosh V., Rathkolb, Birgit, Wolf, Eckhard, Hrabě de Angelis, Martin, Bäuerle, Tobias, Dietel, Barbara, Wagner, Carsten A., Amann, Kerstin, Eckardt, Kai-Uwe, Aronson, Peter S., Anders, Hans Joachim, Knauf, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Innovative Methodology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504458/
https://ncbi.nlm.nih.gov/pubmed/26764204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00488.2015
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