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Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism

Tamm-Horsfall protein (THP) is a glycoprotein expressed exclusively in thick ascending limbs (TAL) of the kidney. We recently described a novel protective role of THP against acute kidney injury (AKI) via downregulation of inflammation in the outer medulla. Our current study investigates the mechani...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: El-Achkar, Tarek M., McCracken, Ruth, Rauchman, Michael, Heitmeier, Monique R., Al-Aly, Ziyad, Dagher, Pierre C., Wu, Xue-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504439/
https://ncbi.nlm.nih.gov/pubmed/21228114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00621.2010
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