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Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression

Tamm-Horsfall protein (THP) is a glycoprotein with unclear functions expressed exclusively in thick ascending limbs (TAL) of the kidney. Its role in ischemic acute kidney injury is uncertain, with previous data suggesting a possible negative effect by enhancing cast formation and promoting inflammat...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: El-Achkar, Tarek M., Wu, Xue-Ru, Rauchman, Michael, McCracken, Ruth, Kiefer, Susan, Dagher, Pierre C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504389/
https://ncbi.nlm.nih.gov/pubmed/18495803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00083.2008
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