Φορτώνει......
Elevated systemic TGF-β impairs aortic vasomotor function through activation of NADPH oxidase-driven superoxide production and leads to hypertension, myocardial remodeling, and increased plaque formation in apoE(−/−) mice
The role of circulating, systemic TGF-β levels in endothelial function is not clear. TGF-β(1) may cause endothelial dysfunction in apolipoprotein E-deficient (apoE(−/−)) mice via stimulation of reactive oxygen species (ROS) production by the NADPH oxidase (NOX) system and aggravate aortic and heart...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Am J Physiol Heart Circ Physiol |
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Κύριοι συγγραφείς: | , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
American Physiological Society
2010
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5504387/ https://ncbi.nlm.nih.gov/pubmed/20511416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01042.2009 |
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