Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Hypertension increases cerebrovascular oxidative stress and inflammation and impairs vasomotor function. These pathological alterations lead to dysregulation of cerebral blood flow and exacerbate atherogenesis, increasing the morbidity of ischaemic cerebrovascular diseases an...

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Autori principali: Toth, Peter, Csiszar, Anna, Sosnowska, Danuta, Tucsek, Zsuzsanna, Cseplo, Peter, Springo, Zsolt, Tarantini, Stefano, Sonntag, William E, Ungvari, Zoltan, Koller, Akos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623058/
https://ncbi.nlm.nih.gov/pubmed/23194285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12079
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