Treatment with the cytochrome P450 ω-hydroxylase inhibitor HET0016 attenuates cerebrovascular inflammation, oxidative stress and improves vasomotor function in spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Hypertension increases cerebrovascular oxidative stress and inflammation and impairs vasomotor function. These pathological alterations lead to dysregulation of cerebral blood flow and exacerbate atherogenesis, increasing the morbidity of ischaemic cerebrovascular diseases an...

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Main Authors: Toth, Peter, Csiszar, Anna, Sosnowska, Danuta, Tucsek, Zsuzsanna, Cseplo, Peter, Springo, Zsolt, Tarantini, Stefano, Sonntag, William E, Ungvari, Zoltan, Koller, Akos
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623058/
https://ncbi.nlm.nih.gov/pubmed/23194285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12079
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