Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation

TLR4 in intestinal epithelial cells has been shown both inflammatory and homeostatic roles following binding of its cognate ligand lipopolysaccharide (LPS). TWEAK-Fn14 axis plays an important role in pathologies caused by excessive or abnormal inflammatory responses. This study aimed to evaluate pot...

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Foilsithe in:Front Cell Infect Microbiol
Main Authors: Qi, Xuefeng, Qin, Lijuan, Du, Ruijing, Chen, Yungang, Lei, Mingzhu, Deng, Meiyu, Wang, Jingyu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Microbiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504244/
https://ncbi.nlm.nih.gov/pubmed/28744451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00315
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