A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

The absence of pathological hallmarks of progressive multiple sclerosis (MS) in commonly used rodent models of experimental autoimmune encephalomyelitis (EAE) hinders the development of adequate treatments for progressive disease. Work reviewed here shows that such hallmarks are present in the EAE m...

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Publicado en:Front Immunol
Autores principales: ’t Hart, Bert A., Dunham, Jordon, Faber, Bart W., Laman, Jon D., van Horssen, Jack, Bauer, Jan, Kap, Yolanda S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504154/
https://ncbi.nlm.nih.gov/pubmed/28744286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00804
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