A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model

The absence of pathological hallmarks of progressive multiple sclerosis (MS) in commonly used rodent models of experimental autoimmune encephalomyelitis (EAE) hinders the development of adequate treatments for progressive disease. Work reviewed here shows that such hallmarks are present in the EAE m...

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Udgivet i:Front Immunol
Main Authors: ’t Hart, Bert A., Dunham, Jordon, Faber, Bart W., Laman, Jon D., van Horssen, Jack, Bauer, Jan, Kap, Yolanda S.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504154/
https://ncbi.nlm.nih.gov/pubmed/28744286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00804
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