Identification of Non-Nucleoside Inhibitors of the Respiratory Syncytial Virus Polymerase Complex

Respiratory syncytial virus (RSV) represents a threat to infants, the elderly, and the immunocompromised. RSV entry blockers are in clinical trials, but escape mutations challenge their potential. In search of RSV inhibitors, we have integrated a signature resistance mutation into are combinant RSV...

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Publicado en:J Med Chem
Main Authors: Jiménez-Somarribas, Alberto, Mao, Shuli, Yoon, Jeong-Joong, Weisshaar, Marco, Cox, Robert M., Marengo, Jose R., Mitchell, Deborah G., Morehouse, Zachary P., Yan, Dan, Solis, Ivan, Liotta, Dennis C., Natchus, Michael G., Plemper, Richard K.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504085/
https://ncbi.nlm.nih.gov/pubmed/28245119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b01568
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