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Detection of KRAS Exon 2 Mutations in Circulating Tumor Cells Isolated by the ISET System from Patients with RAS Wild Type Metastatic Colorectal Cancer()

INTRODUCTION: The presence of KRAS mutations in patients with metastatic colorectal cancer (mCRC) predicts poor response to agents targeting the EGFR. Even in patients with RAS wild type (WT) tumors, resistance eventually develops due to multiple mechanisms, including the expansion of previously und...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Matikas, Alexios, Voutsina, Alexandra, Lagoudaki, Eleni, Hatzidaki, Dora, Trypaki, Maria, Stoupis, Giannis, Tzardi, Maria, Mavroudis, Dimitrios, Georgoulias, Vasilios
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503828/
https://ncbi.nlm.nih.gov/pubmed/28692881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.06.005
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