NRSF-dependent epigenetic mechanisms contribute to programming of stress-sensitive neurons by neonatal experience, promoting resilience

Resilience to stress-related emotional disorders is governed in part by early-life experiences. Here we demonstrate experience-dependent re-programming of stress-sensitive hypothalamic neurons, which takes place through modification of neuronal gene expression via epigenetic mechanisms. Specifically...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Psychiatry
Prif Awduron: Singh-Taylor, A, Molet, J, Jiang, S, Korosi, A, Bolton, J L, Noam, Y, Simeone, K, Cope, J, Chen, Y, Mortazavi, A, Baram, T Z
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503824/
https://ncbi.nlm.nih.gov/pubmed/28070121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.240
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