Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Therapeutic antibodies are effective for tumor immunotherapy and exhibit prominent clinical effects. All approved antibody therapeutics utilize IgG as the molecular format. Antibody-dependent cell-mediated cytotoxicity (ADCC) is a key mechanism for tumor cell killing by antibodies. For IgG antibodie...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Li, Bingyu, Xu, Lijun, Tao, Fei, Xie, Kun, Wu, Zhiqiang, Li, You, Li, Jie, Chen, Kaiming, Pi, Chenyu, Mendelsohn, Andrew, Larrick, James W., Gu, Hua, Fang, Jianmin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503618/
https://ncbi.nlm.nih.gov/pubmed/28454118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17000
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