Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Therapeutic antibodies are effective for tumor immunotherapy and exhibit prominent clinical effects. All approved antibody therapeutics utilize IgG as the molecular format. Antibody-dependent cell-mediated cytotoxicity (ADCC) is a key mechanism for tumor cell killing by antibodies. For IgG antibodie...

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Publicado en:Oncotarget
Autores principales: Li, Bingyu, Xu, Lijun, Tao, Fei, Xie, Kun, Wu, Zhiqiang, Li, You, Li, Jie, Chen, Kaiming, Pi, Chenyu, Mendelsohn, Andrew, Larrick, James W., Gu, Hua, Fang, Jianmin
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503618/
https://ncbi.nlm.nih.gov/pubmed/28454118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17000
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