Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo

Therapeutic antibodies are effective for tumor immunotherapy and exhibit prominent clinical effects. All approved antibody therapeutics utilize IgG as the molecular format. Antibody-dependent cell-mediated cytotoxicity (ADCC) is a key mechanism for tumor cell killing by antibodies. For IgG antibodie...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Li, Bingyu, Xu, Lijun, Tao, Fei, Xie, Kun, Wu, Zhiqiang, Li, You, Li, Jie, Chen, Kaiming, Pi, Chenyu, Mendelsohn, Andrew, Larrick, James W., Gu, Hua, Fang, Jianmin
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503618/
https://ncbi.nlm.nih.gov/pubmed/28454118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17000
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