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Trefoil factor 3 mediation of oncogenicity and chemoresistance in hepatocellular carcinoma is AKT-BCL-2 dependent

The efficacious treatment of hepatocellular carcinoma (HCC) remains a challenge, partially being attributed to intrinsic chemoresistance. Previous reports have observed increased TFF3 expression in HCC. Herein, we investigated the functional role of TFF3 in progression of HCC, and in both intrinsic...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: You, Ming-Liang, Chen, Yi-Jun, Chong, Qing-Yun, Wu, Ming-Ming, Pandey, Vijay, Chen, Ru-Mei, Liu, Liang, Ma, Lan, Wu, Zheng-Sheng, Zhu, Tao, Lobie, Peter E
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503616/
https://ncbi.nlm.nih.gov/pubmed/28445151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16950
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