The Bruton's tyrosine kinase inhibitor ibrutinib exerts immunomodulatory effects through regulation of tumor-infiltrating macrophages

The Bruton's tyrosine kinase (Btk) inhibitor ibrutinib has demonstrated promising efficacy in a variety of hematologic malignancies. However, the precise mechanism of action of the drug remains to be fully elucidated. Tumor-infiltrating macrophages presented in the tumor microenvironment have b...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ping, Lingyan, Ding, Ning, Shi, Yunfei, Feng, Lixia, Li, Jiao, Liu, Yalu, Lin, Yufu, Shi, Cunzhen, Wang, Xing, Pan, Zhengying, Song, Yuqin, Zhu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503608/
https://ncbi.nlm.nih.gov/pubmed/28424405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16836
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