Low-density lipoprotein receptor-related protein 6 is a novel coreceptor of protease-activated receptor-2 in the dynamics of cancer-associated β-catenin stabilization

Protease-activated receptor-2 (PAR(2)) plays a central role in cancer; however, the molecular machinery of PAR(2)-instigated tumors remains to be elucidated. We show that PAR(2) is a potent inducer of β-catenin stabilization, a core process in cancer biology, leading to its transcriptional activity....

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Publicado en:Oncotarget
Autores principales: Nag, Jeetendra Kumar, Kancharla, Arun, Maoz, Myriam, Turm, Hagit, Agranovich, Daniel, Gupta, Chhedi Lal, Uziely, Beatrice, Bar-Shavit, Rachel
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503561/
https://ncbi.nlm.nih.gov/pubmed/28418856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16246
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