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Protease-activated Receptor-1 (PAR1) Acts via a Novel Gα(13)-Dishevelled Axis to Stabilize β-Catenin Levels
We have previously shown a novel link between hPar-1 (human protease-activated receptor-1) and β-catenin stabilization. Although it is well recognized that Wnt signaling leads to β-catenin accumulation, the role of PAR1 in the process is unknown. We provide here evidence that PAR1 induces β-catenin...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2865281/ https://ncbi.nlm.nih.gov/pubmed/20223821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.072843 |
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