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Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms

The emergence of influenza drug resistance has become of particular interest as current planning for an influenza pandemic involves using massive amounts of antiviral drugs. We use semi-stochastic simulations to examine the emergence of drug resistant mutants during the course of a single infection...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Dobrovolny, Hana M., Beauchemin, Catherine A. A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503263/
https://ncbi.nlm.nih.gov/pubmed/28700622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180582
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