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Modelling the emergence of influenza drug resistance: The roles of surface proteins, the immune response and antiviral mechanisms

The emergence of influenza drug resistance has become of particular interest as current planning for an influenza pandemic involves using massive amounts of antiviral drugs. We use semi-stochastic simulations to examine the emergence of drug resistant mutants during the course of a single infection...

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Veröffentlicht in:PLoS One
Hauptverfasser: Dobrovolny, Hana M., Beauchemin, Catherine A. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503263/
https://ncbi.nlm.nih.gov/pubmed/28700622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180582
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