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“Bad Luck Mutations”: DNA Mutations Are not the Whole Answer to Understanding Cancer Risk

It has been proposed that many human cancers are generated by intrinsic mechanisms that produce “Bad Luck” mutations by the proliferation of organ-specific adult stem cells. There have been serious challenges to this interpretation, including multiple extrinsic factors thought to be correlated with...

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Publicat a:Dose Response
Autors principals: Trosko, James E., Carruba, Giuseppe
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502948/
https://ncbi.nlm.nih.gov/pubmed/28717349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1559325817716585
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