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Lysophosphatidic Acid-Induced RhoA Signaling and Prolonged Macrophage Infiltration Worsens Fibrosis and Fatty Infiltration Following Rotator Cuff Tears

Previous studies have suggested that macrophage-mediated chronic inflammation is involved in the development of rotator cuff muscle atrophy and degeneration following massive tendon tears. Increased RhoA signaling has been reported in chronic muscle degeneration, such as muscular dystrophy. However,...

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Pubblicato in:J Orthop Res
Autori principali: Davies, Michael R., Lee, Lawrence, Feeley, Brian T., Kim, Hubert T., Liu, Xuhui
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502767/
https://ncbi.nlm.nih.gov/pubmed/27505847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.23384
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