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Changing the invariant proline-30 of rat and Drosophila melanogaster cytochromes c to alanine or valine destabilizes the heme crevice more than the overall conformation.

Drosophila melanogaster and rat cytochromes c in which proline-30 was converted to alanine or valine were expressed in a strain of baker's yeast, Saccharomyces cerevisiae, where they sustained aerobic growth. The mutations had no significant effect on the spectra or redox potentials but altered...

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Sonraí Bibleagrafaíochta
Main Authors: Koshy, T I, Luntz, T L, Schejter, A, Margoliash, E
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1990
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC55026/
https://ncbi.nlm.nih.gov/pubmed/2174161
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC55026/
https://ncbi.nlm.nih.gov/pubmed/2174161