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Uncovering BRD4 hyperphosphorylation associated with cellular transformation in NUT midline carcinoma
The epigenetic reader BRD4 plays a vital role in transcriptional regulation, cellular growth control, and cell-cycle progression. Dysregulation of BRD4 function has been implicated in the pathogenesis of a wide range of cancers. However, how BRD4 is regulated to maintain its normal function in healt...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502625/ https://ncbi.nlm.nih.gov/pubmed/28630312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1703071114 |
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