Reconstitution of simian virus 40 DNA replication with purified proteins.

Replication of plasmid DNA molecules containing the simian virus 40 (SV40) origin of DNA replication has been reconstituted with seven highly purified cellular proteins plus the SV40 large tumor (T) antigen. Initiation of DNA synthesis is absolutely dependent upon T antigen, replication protein A, a...

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Bibliographic Details
Main Authors: Weinberg, D H, Collins, K L, Simancek, P, Russo, A, Wold, M S, Virshup, D M, Kelly, T J
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC55025/
https://ncbi.nlm.nih.gov/pubmed/2174160
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