Reconstitution of simian virus 40 DNA replication with purified proteins.

Replication of plasmid DNA molecules containing the simian virus 40 (SV40) origin of DNA replication has been reconstituted with seven highly purified cellular proteins plus the SV40 large tumor (T) antigen. Initiation of DNA synthesis is absolutely dependent upon T antigen, replication protein A, a...

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Autores principales: Weinberg, D H, Collins, K L, Simancek, P, Russo, A, Wold, M S, Virshup, D M, Kelly, T J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55025/
https://ncbi.nlm.nih.gov/pubmed/2174160
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