Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription

The role of AP-1 transcription factors in early B cell development and function is still incompletely characterized. Here we address the role of Fra-2 in B cell differentiation. Deletion of Fra-2 leads to impaired B cell proliferation in the bone marrow. In addition, IL-7–stimulated pro–B cell cultu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Exp Med
Main Authors: Ubieta, Kenia, Garcia, Mireia, Grötsch, Bettina, Uebe, Steffen, Weber, Georg F., Stein, Merle, Ekici, Arif, Schett, Georg, Mielenz, Dirk, Bozec, Aline
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502419/
https://ncbi.nlm.nih.gov/pubmed/28566276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160514
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker