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Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription
The role of AP-1 transcription factors in early B cell development and function is still incompletely characterized. Here we address the role of Fra-2 in B cell differentiation. Deletion of Fra-2 leads to impaired B cell proliferation in the bone marrow. In addition, IL-7–stimulated pro–B cell cultu...
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| 出版年: | J Exp Med |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502419/ https://ncbi.nlm.nih.gov/pubmed/28566276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160514 |
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