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Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys

Synthetic cannabinoids have been prohibited due to abuse liability and toxicity. Four such synthetic cannabinoids, AM-2201 ([1-(5-fluoropentyl)indol-3-yl]-naphthalen-1-ylmethanone), CP-47,497 (2-[(1R,3S)-3-hydroxycyclohexyl]-5-(2-methyloctan-2-yl)phenol), JWH-122 [(4-methylnaphthalen-1-yl)-(1-pentyl...

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Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Hruba, Lenka, McMahon, Lance R.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502382/
https://ncbi.nlm.nih.gov/pubmed/28533288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.240572
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