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Single Particle Observation of SV40 VP1 Polyanion-Induced Assembly Shows that Substrate Size and Structure Modulate Capsid Geometry
Simian virus 40 capsid protein (VP1) is a unique system for studying substrate-dependent assembly of a nanoparticle. Here, we investigate a simplest case of this system where 12 VP1 pentamers and a single polyanion, e.g. RNA, form a T=1 particle. To test the roles of polyanion substrate length and s...
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| Izdano u: | ACS Chem Biol |
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| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502116/ https://ncbi.nlm.nih.gov/pubmed/28323402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01066 |
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