EGFR-mediated Macrophage Activation Promotes Colitis-associated Tumorigenesis

Epidermal growth factor receptor (EGFR) signaling is a known mediator of colorectal carcinogenesis. Studies have focused on the role of EGFR signaling in epithelial cells, although the exact nature of the role of EGFR in colorectal carcinogenesis remains a topic of debate. Here, we present evidence...

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Pubblicato in:Oncogene
Autori principali: Hardbower, Dana M., Coburn, Lori A., Asim, Mohammad, Singh, Kshipra, Sierra, Johanna C., Barry, Daniel P., Gobert, Alain P., Piazuelo, M. Blanca, Washington, M. Kay, Wilson, Keith T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501754/
https://ncbi.nlm.nih.gov/pubmed/28263971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.23
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