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The Apolipoprotein E-Mimetic Peptide COG112 Inhibits NF-κB Signaling, Proinflammatory Cytokine Expression, and Disease Activity in Murine Models of Colitis

Inflammatory bowel disease (IBD), consisting of Crohn's disease and ulcerative colitis, is a source of substantial morbidity and remains difficult to treat. New strategies for beneficial anti-inflammatory therapies would be highly desirable. Apolipoprotein (apo) E has immunomodulatory effects a...

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Detalhes bibliográficos
Main Authors: Singh, Kshipra, Chaturvedi, Rupesh, Barry, Daniel P., Coburn, Lori A., Asim, Mohammad, Lewis, Nuruddeen D., Piazuelo, M. Blanca, Washington, M. Kay, Vitek, Michael P., Wilson, Keith T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030385/
https://ncbi.nlm.nih.gov/pubmed/21115487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.176719
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