The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System

The R2TP complex, comprising the Rvb1p-Rvb2p AAA-ATPases, Tah1p, and Pih1p in yeast, is a specialized Hsp90 co-chaperone required for the assembly and maturation of multi-subunit complexes. These include the small nucleolar ribonucleoproteins, RNA polymerase II, and complexes containing phosphatidyl...

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Publicat a:Structure
Autors principals: Rivera-Calzada, Angel, Pal, Mohinder, Muñoz-Hernández, Hugo, Luque-Ortega, Juan R., Gil-Carton, David, Degliesposti, Gianluca, Skehel, J. Mark, Prodromou, Chrisostomos, Pearl, Laurence H., Llorca, Oscar
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2017
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Short Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501727/
https://ncbi.nlm.nih.gov/pubmed/28648606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.016
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