Pseudotemporal ordering of single cells reveals metabolic control of postnatal beta-cell proliferation

Pancreatic beta-cell mass for appropriate blood glucose control is established during early postnatal life. Beta-cell proliferative capacity declines postnatally but the extrinsic cues and intracellular signals that cause this decline remain unknown. To obtain a high-resolution map of beta-cell tran...

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Gepubliceerd in:Cell Metab
Hoofdauteurs: Zeng, Chun, Mulas, Francesca, Sui, Yinghui, Guan, Tiffany, Miller, Nathanael, Tan, Yuliang, Liu, Fenfen, Jin, Wen, Carrano, Andrea C., Huising, Mark O., Shirihai, Orian S., Yeo, Gene W., Sander, Maike
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501713/
https://ncbi.nlm.nih.gov/pubmed/28467932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.04.014
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