Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection

Schistosomiasis is a chronic parasitic disease caused by sexually dimorphic blood flukes of the genus Schistosoma. Praziquantel (PZQ) is the only drug widely available to treat the disease but does not kill juvenile parasites. Here we report the use of next generation sequencing to study the transcr...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Sanchez, Melissa C., Krasnec, Katina V., Parra, Amalia S., von Cabanlong, Christian, Gobert, Geoffrey N., Umylny, Boris, Cupit, Pauline M., Cunningham, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501684/
https://ncbi.nlm.nih.gov/pubmed/28650976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005691
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