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Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection

Schistosomiasis is a chronic parasitic disease caused by sexually dimorphic blood flukes of the genus Schistosoma. Praziquantel (PZQ) is the only drug widely available to treat the disease but does not kill juvenile parasites. Here we report the use of next generation sequencing to study the transcr...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Sanchez, Melissa C., Krasnec, Katina V., Parra, Amalia S., von Cabanlong, Christian, Gobert, Geoffrey N., Umylny, Boris, Cupit, Pauline M., Cunningham, Charles
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501684/
https://ncbi.nlm.nih.gov/pubmed/28650976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005691
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