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The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein

Mutations in the immunoglobulin superfamily, member 1 gene (IGSF1/Igsf1) cause an X-linked form of central hypothyroidism. The canonical form of IGSF1 is a transmembrane glycoprotein with 12 immunoglobulin (Ig) loops. The protein is co-translationally cleaved into two sub-domains. The carboxyl-termi...

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Publicat a:PLoS One
Autors principals: Wang, Ying, Brûlé, Emilie, Silander, Tanya, Bak, Beata, Joustra, Sjoerd D., Bernard, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501590/
https://ncbi.nlm.nih.gov/pubmed/28686733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180731
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