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The short mRNA isoform of the immunoglobulin superfamily, member 1 gene encodes an intracellular glycoprotein
Mutations in the immunoglobulin superfamily, member 1 gene (IGSF1/Igsf1) cause an X-linked form of central hypothyroidism. The canonical form of IGSF1 is a transmembrane glycoprotein with 12 immunoglobulin (Ig) loops. The protein is co-translationally cleaved into two sub-domains. The carboxyl-termi...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501590/ https://ncbi.nlm.nih.gov/pubmed/28686733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180731 |
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