The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

The mAb A33 detects a membrane antigen that is expressed in normal human colonic and small bowel epithelium and >95% of human colon cancers. It is absent from most other human tissues and tumor types. The murine A33 mAb has been shown to target colon cancer in clinical trials, and the therapeutic po...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Heath, Joan K., White, Sara J., Johnstone, Cameron N., Catimel, Bruno, Simpson, Richard J., Moritz, Robert L., Tu, Guo-Fen, Ji, Hong, Whitehead, Robert H., Groenen, Leo C., Scott, Andrew M., Ritter, Gerd, Cohen, Leonard, Welt, Sydney, Old, Lloyd J., Nice, Edouard C., Burgess, Antony W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1997
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.469
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