The human A33 antigen is a transmembrane glycoprotein and a novel member of the immunoglobulin superfamily

The mAb A33 detects a membrane antigen that is expressed in normal human colonic and small bowel epithelium and >95% of human colon cancers. It is absent from most other human tissues and tumor types. The murine A33 mAb has been shown to target colon cancer in clinical trials, and the therapeutic po...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Heath, Joan K., White, Sara J., Johnstone, Cameron N., Catimel, Bruno, Simpson, Richard J., Moritz, Robert L., Tu, Guo-Fen, Ji, Hong, Whitehead, Robert H., Groenen, Leo C., Scott, Andrew M., Ritter, Gerd, Cohen, Leonard, Welt, Sydney, Old, Lloyd J., Nice, Edouard C., Burgess, Antony W.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1997
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9012807/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.2.469
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