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Caspase-6 mediates resistance against Burkholderia pseudomallei infection and influences the expression of detrimental cytokines

Caspase-6 is a member of the executioner caspases and known to play a role in innate and adaptive immune processes. However, its role in infectious diseases has rarely been addressed yet. We here examined the impact of caspase-6 in an in vivo infection model using the Gram-negative rod Burkholderia...

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Pubblicato in:PLoS One
Autori principali: Bartel, Alexander, Göhler, André, Hopf, Verena, Breitbach, Katrin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501493/
https://ncbi.nlm.nih.gov/pubmed/28686630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180203
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