Caspase-1-Dependent and -Independent Cell Death Pathways in Burkholderia pseudomallei Infection of Macrophages

The cytosolic pathogen Burkholderia pseudomallei and causative agent of melioidosis has been shown to regulate IL-1β and IL-18 production through NOD-like receptor NLRP3 and pyroptosis via NLRC4. Downstream signalling pathways of those receptors and other cell death mechanisms induced during B. pseu...

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Detalhes bibliográficos
Main Authors: Bast, Antje, Krause, Kathrin, Schmidt, Imke H. E., Pudla, Matsayapan, Brakopp, Stefanie, Hopf, Verena, Breitbach, Katrin, Steinmetz, Ivo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953413/
https://ncbi.nlm.nih.gov/pubmed/24626296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003986
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