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Modeling the causal regulatory network by integrating chromatin accessibility and transcriptome data
Cell packs a lot of genetic and regulatory information through a structure known as chromatin, i.e. DNA is wrapped around histone proteins and is tightly packed in a remarkable way. To express a gene in a specific coding region, the chromatin would open up and DNA loop may be formed by interacting e...
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| Publicado no: | Natl Sci Rev |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501464/ https://ncbi.nlm.nih.gov/pubmed/28690910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nww025 |
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