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4-Fluoroprolines: Conformational Analysis and Effects on the Stability and Folding of Peptides and Proteins

Proline is unique among proteinogenic amino acids because a pyrrolidine ring links its amino group to its side chain. This heterocycle constrains the conformations of the main chain and thus templates particular secondary structures. Proline residues undergo post-translational modification at the 4-...

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Detalhes bibliográficos
Publicado no:Top Heterocycl Chem
Main Authors: Newberry, Robert W., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501414/
https://ncbi.nlm.nih.gov/pubmed/28690684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/7081_2015_196
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