The role of interfacial lipids in stabilising membrane protein oligomers

Oligomerisation of membrane proteins in response to lipid binding plays a critical role in many cell-signaling pathways 1 but is often difficult to define 2 or predict 3. Here we develop a mass spectrometry platform to determine simultaneously presence of interfacial lipids and oligomeric stability...

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Udgivet i:Nature
Main Authors: Gupta, Kallol, Donlan, Joseph A.C., Hopper, Jonathan T.S., Uzdavinys, Povilas, Landreh, Michael, Struwe, Weston B., Drew, David, Baldwin, Andrew J., Stansfeld, Phillip J., Robinson, Carol V.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501331/
https://ncbi.nlm.nih.gov/pubmed/28077870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20820
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