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Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus

Epigenetics is involved in the altered expression of gene networks that underlie insulin resistance and insufficiency. Major genes controlling β-cell differentiation and function, such as PAX4, PDX1, and GLP1 receptor, are epigenetically controlled. Epigenetics can cause insulin resistance through i...

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Bibliografische gegevens
Gepubliceerd in:Epigenetics
Hoofdauteurs: Sommese, Linda, Zullo, Alberto, Mancini, Francesco Paolo, Fabbricini, Rossella, Soricelli, Andrea, Napoli, Claudio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501211/
https://ncbi.nlm.nih.gov/pubmed/28059593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1278097
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