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Clinical relevance of epigenetics in the onset and management of type 2 diabetes mellitus
Epigenetics is involved in the altered expression of gene networks that underlie insulin resistance and insufficiency. Major genes controlling β-cell differentiation and function, such as PAX4, PDX1, and GLP1 receptor, are epigenetically controlled. Epigenetics can cause insulin resistance through i...
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| Publicado no: | Epigenetics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501211/ https://ncbi.nlm.nih.gov/pubmed/28059593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1278097 |
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